Xalcort 6 - Tablet Deflazacort - 6mg 10 Tablet(s) / Strip Beacon Pharmaceuticals PLC Introduction: Xalcort 6 belongs to a group of medicines called steroids. It is used for treatment of various diseases and conditions such as allergic conditions, asthma, cancer, rheumatic disorder, and skin and eye disorders. Xalcort 6 works by inhibiting the release of substances that cause swelling or by changing how the immune system works. It can be taken in an empty stomach or after food. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. Taking this medicine can cause few... Uses of Xalcort 6: Severe allergic reactionsAllergic conditionsAsthmaCancerRheumatic disorderSkin disordersEye disorders Side effects of Xalcort 6: Increased appetiteFrequent urge to urinateFacial swellingAbnormal hair growthCushing syndromeCough How to use Xalcort 6: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xalcort 6 may be taken with or without food, but it is better to take it at a fixed time. How Xalcort 6 works: . Indication: Allergic and inflammatory disorders Adult Dose: Oral Allergic and inflammatory disorders Adult: Initially, up to 120 mg daily. Maintenance: 3-18 mg/day. Hepatic impairment: Dose reductions may be needed. Child Dose: Oral Allergic and inflammatory disorders Child: 0.25-1.5 mg/kg/day given on alternate days. Contraindication: Systemic infection; live virus vaccines in those receiving immunosuppressive doses. Mode of Action: Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone. Precaution: Adrenal suppression and infection, child, adolescents, elderly, history of TB and steroid myopathy, hypertension, recent MI, CHF, liver failure, renal impairment, DM and glaucoma (including family history), osteoporosis, corneal perforation, severe affective disorders, epilepsy, peptic ulcer, hypothyroidism, pregnancy and lactation. Side Effect: GI disturbances, musculoskeletal, endocrine, neuropsychiatric, ophthalmic, fluid and electrolyte disturbances; susceptible to infection, impaired healing, hypersensitivity, skin atrophy, striae, telangiectasia, acne, myocardial rupture following recent MI, thromboembolism. Pregnancy Category Note: Pregnancy Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus Infants born to mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism Lactation Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for the drug, and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition Interaction: Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, aspirin, barbiturate, ?-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, ?2 sympathomimetics, theophylline, vaccines.