Ulicon - Tablet Ulipristal Acetate - 30mg 1 Tablet(s) / Tablet Eskayef Pharmaceuticals Ltd. Introduction: Ulicon is a medicine used to treat uterine fibroids (a non-cancerous growth in the uterus). It is used for intermittent treatment and pre-operative treatment of uterine fibroid in women of reproductive age. Ulicon reduces symptoms like vaginal bleeding, prolonged periods and lower back pain. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms.... Uses of Ulicon: Uterine fibroids Side effects of Ulicon: Absence of menstrual periodsHeadacheEndometrial hyperplasia How to use Ulicon: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ulicon may be taken with or without food, but it is better to take it at a fixed time. How Ulicon works: Ulicon is a selective progesterone receptor modulator. It works by modifying the action of progesterone (natural female hormone). It is used either before surgery of fibroids or for intermittent (at regular intervals) treatment of fibroids. It helps reduce their size, stops or controls bleeding and increases your red blood cell count. What if you forget to take Ulicon?: If you miss a dose of Ulicon, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Emergency contraception, For pre-operative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age Administration: May be taken with or without food. Adult Dose: Oral Emergency Contraception: One tablet taken orally as soon as possible within 120 hours (5 days) after unprotected intercourse or a known or suspected contraceptive failure. If vomiting occurs within 3 hours of Ulipristal Acetate intake, consideration should be given to repeating the dose. Uterine Fibroids: The treatment consists of 1 tablet of 5 mg to be taken orally once daily for up to 3 months. This 3-month treatment course can be repeated once. Re-treatment should start at the earliest during the second menstruation following the 1st treatment course completion. Treatments should always be started during the 1st week of... Contraindication: Ulipristal Acetate is contraindicated for use in the case of known or suspected pregnancy. Hypersensitivity to ulipristal acetate or to any of the excipients. Genital bleedng or unknown aetiology or for reasons other than uterine fibroids. Uterine, cervical, ovarian or breast cancer. Breastfeeding. Mode of Action: Selective progesterone receptor modulator with antagonistic and partial agonistic effects. When taken immediately before ovulation, postpones follicular rupture. It is thought that the primary mechanism of action for emergency contraception is inhibition or delay of ovulation; however, alterations to the endometrium that may affect implantation may also occur. Precaution: Existing Pregnancy Not indicated for termination of an existing pregnancy. Pregnancy should be excluded before prescribing Ulipristal Acetate. Ectopic Pregnancy A history of ectopic pregnancy is not a contraindication to use of this emergency contraceptive method. Repeated Use Ulipristal Acetate is for occasional use as an emergency contraceptive. It should not replace a regular method of contraception. Repeated use of Ulipristal Acetate within the same menstrual cycle is not recommended, as safety and efficacy of repeat use within the same cycle has not been evaluated. Fertility Following Use A rapid return of fertility is likely following treatment with Ulipristal Acetate... Side Effect: Mood disorders; headache, dizziness; nausea, abdominal pain/discomfort, vomiting; myalgia, back pain; dysmenorrhea, pelvic pain, breast tenderness; fatigue. Interaction: Concomitant administration of medicinal products containing progestagen is not recommended. Also concomitant use of ulipristal acetate and potent CYP3A4 inducers (eg, rifampicin, rifabutin, carbamazepine, oxcarbazepine, phenytoin, fosphenytoin, phenobarbital, primidone, St John´s wort, efzvirenz, nevirapine, long term use of ritonavir) is not recommended.