Synflorix - Injection Pneumococcal Polysaccharide Conjugated Vaccine - 0.5ml 1 Injection(s) / Injection Glaxo SmithKline Pharmaceuticals Ltd Introduction: Synflorix is a medicine used for prevention of invasive diseases caused by pneumococcal bacteria such as pneumonia, meningitis, ear infection, and blood infections. The vaccine helps to protect the body against the diseases that can be caused by pneumococcal bacteria. Synflorix is usually given as an injection into the muscle of the upper arm by a doctor or a nurse. It should not be self-administered. Only one dose is needed for most people. A booster dose can be given 5 years after the first dose. Some common side effects of this medicine include injection site reactions (such as pain, swelling,... Uses of Synflorix: Prevention of pneumonia, meningitis, blood infection & ear infection Side effects of Synflorix: Injection site rednessSleepinessIrritationLoss of appetiteFeverAllergic reactionRashSoreness How to use Synflorix: Your doctor or nurse will give you this medicine. Kindly do not self administer. How Synflorix works: Synflorix is a vaccine which helps develop immunity by initiating a mild infection. This type of infection does not cause illness but stimulates the body's immune system to produce antibodies (proteins) to protect against any future infections. What if you forget to take Synflorix?: If you miss a dose of Synflorix, please consult your doctor. Indication: Active immunization for the prevention of pneumococcal disease, Meningitis, Sepsis, Bacteraemic pneumonia, Pleural empyema, Bacteraemia, Pneumococcal pneumonia Child Dose: Intramuscular Active immunisation against pneumococcal disease Infant 6 wk-6 mth: 3-dose Primary series 1st dose given at 2 mth or at 6 wk of age, with 1-mth interval between doses. A booster dose is recommended at least 6 months after the last priming dose. 2-dose Primary series 2 doses w/ the 1st dose given at 2 mth of age, w/ 2-mth interval between 1st & 2nd dose. Infants 7-11 mth: 2 doses at least 1 mth apart, with the 3rd dose given in the 2nd yr of life. Infant & childn 12 mth-5 yr previously unvaccinated 2 doses w/ at... Contraindication: Hypersensitivity to any component of the vaccine. Febrile illness, acute disease, anaphylactic reaction to a previous dose, severe primary immunodeficiency. Mode of Action: These products convey active immunity via stimulation of production of endogenously produced antibodies . Precaution: Severe renal, hepatic, cardiac, vascular &/or pulmonary dysfunction. Patients on immunosuppressants may be unable to attain required antibody titres. Pregnancy & lactation. Efficacy may be reduced in multiple myeloma, Hodgkin's and non-Hogkin's lymphoma, especially during treatment and in chronic alcoholism. Vaccine should be given 2 wk before starting immunosuppressive treatment or at least 3 mth after treatment completion. Side Effect: Local inj site reactions, warmth, erythema & swelling; fever, headache, malaise. Interaction: Adequate response may not be elicited w/ immunosuppressants.