Spusoft 300 - Capsule Erdosteine - 300mg 10 Capsule(s) / Strip Incepta Pharmaceuticals Ltd. Introduction: Spusoft 300 is mucolytic medication. It is used in the treatment of various respiratory tract disorders associated with excessive mucus. Spusoft 300 should be taken with or without food. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. You must consult with the doctor if the condition does not get improved after... Uses of Spusoft 300: respiratory tract disorders associated with viscid mucus Side effects of Spusoft 300: Flushing (sense of warmth in the face, ears, neck and trunk)Increased sweatingNauseaVertigoVomiting How to use Spusoft 300: Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Spusoft 300 may be taken with or without food, but it is better to take it at a fixed time. How Spusoft 300 works: Spusoft 300 is a mucolytic agent. It works by breaking up mucus (phlegm), making it easier to cough out. Indication: Symptomatic treatment of acute exacerbations of, chronic bronchitis, in adults as an expectorant. Administration: The capsules must be swallowed whole with a glass of water. Adult Dose: Oral As a mucolytic Adult: 300 mg bid. Max duration: 10 days. Hepatic Failure Since there are no data in patients with severe liver failure, the use of erdosteine is not recommended in these patients. Mild to Moderate Hepatic Failure Dose should be reduced Renal Dose: Since there are no data in patients with creatinine clearance <25ml/min, the use of erdosteine is not recommended in these patients. Contraindication: Hypersensitivity to the active substance or to any of the other excipients. Active peptic ulcer. Mode of Action: Erdosteine contains two sulfhydryl groups, which are freed after metabolic transformation in the liver. The liberated sulfhydryl groups break the disulphide bonds, which hold the glycoprotein fibres of mucus together. This makes the bronchial secretions more fluid and enhances elimination. Precaution: Pregnancy, lactation. Side Effect: Epigastralgia, nausea, vomiting, loose stools, spasmodic colitis, headache.