Rupanex - Tablet Rupatadine - 10mg 10 Tablet(s) / Strip Sharif Pharmaceuticals Ltd. Introduction: Rupanex belongs to a group of medicines called antihistamines. It is used in the treatment of various allergic conditions. It relieves symptoms like itching, swelling and rashes. Rupanex should be taken with or without food. The dose may vary depending on what you are taking it for. Take it as it has been prescribed by your doctor. You may need this medicine only on days you have symptoms, or you may need to take it every day to prevent symptoms from happening. If you stop taking it earlier than advised, your symptoms may come back. This medicine is generally very... Uses of Rupanex: Allergic conditions Side effects of Rupanex: Sleepiness How to use Rupanex: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rupanex may be taken with or without food, but it is better to take it at a fixed time. How Rupanex works: Rupanex is an antihistaminic medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body. What if you forget to take Rupanex?: If you miss a dose of Rupanex, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Allergic rhinitis, Chronic idiopathic urticaria Adult Dose: Oral Allergic rhinitis; Chronic idiopathic urticaria Adult: 10 mg (1 tablet) once daily. Child Dose: Oral Allergic rhinitis; Chronic idiopathic urticaria Tablet Child > 12 years: 10 mg (1 tablet) once daily. Children: Use of Rupatadine is not recommended in patients less than 12 years of age. Syrup: Children aged 2 to 11 years: Children weighing 10 kg to less than 25 kg: 1/2 teaspoonful (2.5 ml) syrup once a day with or without food. Children weighing 25 kg or more: 1 teaspoonful (5ml) of syrup once a day with or without food. Contraindication: Hypersensitivity. Avoid alcohol. Mode of Action: Rupatadine acts as a long-acting, non-sedative antagonist at histaminergic H1-receptors. Rupatadine also antagonises the platelet-activating factor (PAF). Both histamine and PAF cause bronchoconstriction and lead to an increase in the vascular permeability, acting as mediators in the inflammatory process. Precaution: Renal or hepatic insufficiency. May impair ability to drive or operate machinery. Pregnancy, lactation. Elderly, children <12 yr. Side Effect: Headache, somnolence, fatigue/asthenia. Interaction: Increased CNS depressant effects when used with CNS depressants or alcohol.