Orofer - Syrup Elemental Iron + Folic Acid + Vitamin C + Zinc - 47mg+500mcg+22.5mg 1 100ml bot(s) / 100ml bot Unimed Unihealth Pharmaceuticals Ltd. Indication: Iron, Folic acid, Vitamin-C deficiency, Pregnancy and lactation Administration: For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation Adult Dose: 1 tablet daily. In more severe cases, 2 tablets a day may be required. Contraindication: Contraindicated in patients with a known hypersensitivity to any of the ingredients of this product. Mode of Action: Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin. Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy. Zinc: Cofactor in over... Precaution: Caution should be taken in the conditions where there is a risk of iron overload, such as haemochromatosis, thalassemia, haemosiderosis or haemolytic anaemia. Lactation: Present in breast milk, use caution Side Effect: A few side-effects of oral iron preparations, including nausea, vomiting, constipation or diarrhoea may occur. Interaction: Elemental iron: Antacids may decrease the absorption of carbonyl iron. Folic acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations. Vit C: Deferroxamine, hormonal contraceptives, flufenazine, warfarin, elemental iron, salicylates, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.