Orobenz Pain Gargle - mouthwash Benzydamine Mouth prep - 0.15%w/v 1 250ml Bottle(s) / 250ml Bottle Mundipharma (BD) Introduction: Orobenz Pain Gargle is a pain relieving medicine. It is used to relieve pain, discomfort, and inflammation of the mouth, gums, and throat. It provides relief from pain and swelling and aids in speeding up the healing process. Orobenz Pain Gargle should be used strictly as advised by your doctor. Use it in the dose and duration as directed by your doctor. You should not use more medicine or apply it more often than prescribed by your doctor. This will not make it work any faster and may increase side effects. It is usually safe with little or no side... Uses of Orobenz Pain Gargle: Pain relief Side effects of Orobenz Pain Gargle: No common side effects seen How to use Orobenz Pain Gargle: Check the label before use. Take the mouthwash in the quantity as advised by your doctor and put it in your mouth. Swish for 30 seconds to 1 minute and spit it. Do not swallow. Avoid eating, drinking, or smoking for at least 30 minutes after rinsing. How Orobenz Pain Gargle works: Orobenz Pain Gargle is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling) in the mouth. What if you forget to take Orobenz Pain Gargle?: If you miss a dose of Orobenz Pain Gargle, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Pain or irritation of the mouth and throat, Acute Pharyngitis, Radiation-Associated Mucositis Administration: Rinse the 15 ml mouthwash around the mouth or use it as a gargle. After 20 to 30 second, spit it out. Do not swallow the mouthwash. Adult Dose: Mouth/Throat Pain or irritation of the mouth and throat, Acute pharyngitis Adult: Rinse or gargle 15 ml of a 0.15% solution (diluted with water if stinging occurs) every 1½ to 3 hours until remission of pain.. Radiation-Associated Mucositis Gargle or rinse 15 mL in mouth (for 30 seconds, followed by expulsion from mouth) 3-4 times per day Begin treatment 1 day prior to radiation therapy and continue daily during treatment Contraindication: Benzydamine Hydrochloride is contraindicated in subjects with a history of hypersensitivity to any of its components. Mode of Action: Benzydamine Hydrochloride predominantly acts by inhibiting the synthesis of pro inflammatory cytokines like tumour necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β) without largely affecting other pro inflammatory cytokines. Moreover, it is capable of a local anaesthetic effect that may be related to its capability for inhibiting the release of inflammatory mediators like substance P. Precaution: The use of undiluted benzydamine Hydrochloride may produce local irritation manifested by burning sensation in patients with mucosal defects. If necessary, it may be diluted (1:1) with lukewarm water. Since it is absorbed from the oral mucosa and excreted mostly unchanged in the urine, a possibility of its systemic action has to be considered in patients with renal impairment. Side Effect: 1-10% Burning /stinging sensation,Nausea/vomiting,Numbness Frequency Not Defined Cough,Drowsiness,Dry mouth,Headache,Pharyngeal irritation Pregnancy Category Note: Pregnancy Category: Not available. Safety has not been established in pregnant women. Lactation: excretion in milk unknown; use with caution