Moxilocin D - Eye Drop Dexamethasone + Moxifloxacin eye prep - 1 5ml drop(s) / 5ml drop Opsonin Pharma Limited Introduction: Moxilocin D is a prescription medicine having a combination of medicines that is used to treat bacterial eye infections. It stops the growth of bacteria and helps in relieving redness, itching and swelling. Moxilocin D is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning... Uses of Moxilocin D: Bacterial infections Side effects of Moxilocin D: Eye irritationEye discomfort How to use Moxilocin D: This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. How Moxilocin D works: Moxilocin D is a combination of two medicines: Moxifloxacin and Dexamethasone. Moxifloxacin is an antibiotic which prevents bacterial cells from dividing and repairing, thereby killing the bacteria. This treats your eye infection. Dexamethasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen and itchy. Indication: Treatment of ocular infections caused by susceptible microorganisms. Prevention of inflammation & bacterial infection after ocular surgery. Steroid-responsive inflammatory ocular conditions Adult Dose: Ophthalmic One or two drops instilled into the conjunctival sac(s), every 4 to 6 hours. During the initial 24 to 48 hours. The dosage may be increased to 1 or 2 drops every two hours. Frequency must be decreased gradually or warranted by improvement in clinical signs. Care should be taken not to discontinue the therapy prematurely. Contraindication: This eye drop is contraindicated in epithelial herpes simplex keratitis (Dendritic keratitis), vaccinia, varicella, and in many other viral diseases of the conjunctiva and cornea, Mycobacterial infection of the eye and fungal diseases of ocular structures and in individuals hypersensitive to any of the components of the medication. Mode of Action: Dexamethasone is a synthetic glucocorticoid which decreases inflammation by inhibiting the migration of leukocytes and reversal of increased capillary permeability. It suppresses normal immune response. Moxifloxacin inhibits the topoisomerase II (DNA gyrase) and topoisomerase IV required for bacterial DNA replication, transcription, repair and recombination. Precaution: Prolonged use of steroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation. Side Effect: The most frequently reported drug-related undesirable effects seen with moxifloxacin are conjunctival irritation, increased lacrimation, keratitis and papillary conjunctivitis. Secondary Infection