Micoral Gel 15gm - Oral Gel Miconazole 2% Oral Gel - 2% 1 15gm tube(s) / 15gm tube ACI Limited Introduction: Micoral Gel 15gm is an antifungal medicine used to treat fungal infections of the skin. It works by killing the fungus that causes infections such as athlete’s foot, Dhobie Itch, thrush, ringworm and dry, flaky skin. Micoral Gel 15gm should be used in the dose and duration as prescribed by your doctor. This medicine should be used regularly to get the most benefit from it. Do not use more than you needed, it will not clear your condition faster and may only increase the side effects. Skin infections will usually get better after 2 to 6 weeks. Do not use... Uses of Micoral Gel 15gm: Fungal skin infections Side effects of Micoral Gel 15gm: Application site reactions (burning, irritation, itching and redness) How to use Micoral Gel 15gm: This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area. How Micoral Gel 15gm works: Micoral Gel 15gm is an antifungal medication which treats skin infections. It works by killing the fungi on the skin by destroying their cell membrane. What if you forget to take Micoral Gel 15gm?: If you miss a dose of Micoral Gel 15gm, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Oropharyngeal candidiasis, Oral thrush, Denture stomatitis, Fungal infections of the mouth, Throat and gut, Angular cheilitis, Dermatomycoses, Tinea pedis, Tinea corporis, Tinea cruris, Tinea versicolor Administration: Apply on oral lesions and retain in the mouth as long as possible before swallowing. For localised lesions of the mouth, a small amount of gel may be applied directly to the affected area with a clean finger. Adult Dose: Mouth/Throat Oropharyngeal candidiasis, Intestinal candidiasis Adult: The usual dose is 15 mg/kg/day in divided doses. One or two tea spoonfuls (5-10 ml) of gel four times daily. Continue treatment for at least 1 wk after symptoms have disappeared. Localised lesions of mouth: Smear small amount on affected area with clean finger 4 times daily for 5-7 days. Child Dose: Mouth/Throat Oropharyngeal candidiasis Children aged 6 years and over: One tea-spoonful (5 ml) of gel four times daily. Children aged 2-6 years: One tea-spoonful (5 ml) of gel twice daily. Infants under 2 years: Half tea-spoonful (2.5 ml) of gel twice daily. Continue treatment for at least 1 wk after symptoms have disappeared. Localised lesions of mouth: Smear small amount on affected area with clean finger 4 times daily for 5-7 days. Contraindication: Miconazole Oral Gel is contraindicated in patients with known hypersensitivity to any of its components and in patients with liver dysfunction. Mode of Action: Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients. Precaution: Caution is required particularly in infants & young children to ensure that the gel does not obstruct the throat. Lactation: Unknown whether distributed in breast milk, caution advised Side Effect: 1-10% Diarrhea (6%),Nausea (4.6%),Headache (5%),Dysgeusia (2.9%),Upper abdominal pain (2.5%),Vomiting (2.5%) Interaction: May increase anticoagulant effect of warfarin. May increase or prolong the effect of the following drugs: Oral hypoglycaemics (e.g. sulfonylureas), phenytoin, HIV protease inhibitors (e.g. saquinavir), antineoplastic agents (e.g. vinca alkaloids, busulfan, docetaxel), Ca channel blockers (e.g. dihydropyridines, verapamil), immunosuppressive agents (e.g. ciclosporin, tacrolimus, sirolimus), carbamazepine, cilostazol, buspirone, disopyramide, alfentanil, sildenafil, alprazolam, brotizolam, midazolam IV, rifabutin, methylprednisolone, trimetrexate, ebastine and reboxetine. Potentially Fatal: Increased risk of cardiac arrhythmia w/ astemizole, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole, terfenadine. May increase exposure to ergot alkaloids leading to ergotism. May increase the risk of rhabdomyolysis w/ HMG-CoA reductase inhibitors (e.g. simvastatin and...