Mega Forte - Omega-3 fatty acids - 30 Capsule(s) / Box Synergy Bio Care Indication: Dyslipidemia, Hypertriglyceridaemin, Prophylaxis of myocardial infarction Administration: Should be taken with food. Adult Dose: Oral Hypertriglyceridaemia Adult: 4 g once daily 2g twice daily. Secondary prophylaxis of myocardial infarction Adult: 1 g daily. Child Dose: <18 years: Safety and efficacy not established Contraindication: Patients with known hypersensitivity (e.g., anaphylactic reaction) to LOVAZA or any of its components. Mode of Action: The omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid are long-chain n-3 polyunsaturated fatty acids, which compete with arachidonic acid for inclusion in cyclo-oxygenase and lipoxygenase pathways. Their actions include hypolipidaemic action (especially a reduction in plasma triglycerides) by reducing very-low-density lipoproteins; anti-inflammatory action, attributed to effects on leukotriene synthesis; and antiplatelet effect, attributed to effects on prostanoid synthesis, which promote vasodilatation, reduction in platelet aggregation, increased bleeding time and decreased platelet counts. Precaution: Haemorrhagic disorders or those receiving anticoagulants or other drugs that have antithrombotic activity; asthmatic patients sensitive to aspirin. Monitor hepatic function in patients with hepatic impairment, especially if receiving high doses. Lactation: Not known if excreted in breast milk; use caution Side Effect: 1-10% Eructation (4.9%),Infection (4.4%),Flu-like syndrome (3.5%),Dyspepsia (3.1%),Taste perversion (2.7%),Back pain (2.2%),Pain (1.8%),Rash (1.8%),Angina pectoris (1.3%)