Lumex - Eye/Ear Drops Lomefloxacin 0.3% Eye or Ear prep - 0.30% 1 5ml drop(s) / 5ml drop Gaco Pharmaceuticals(G.A Company Ltd) Introduction: Lumex is an antibiotic, used in the treatment of bacterial infections of the eye. It relieves the symptoms of the infection by stopping the further growth of the causative microorganisms. Lumex is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. Avoid skipping any doses and finish the full course of treatment even if you feel better. It may cause burning sensation in the eyes immediately following... Uses of Lumex: Bacterial eye infections Side effects of Lumex: Burning sensation in eye How to use Lumex: This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. How Lumex works: Lumex is an antibiotic. It treats bacterial eye infections by preventing the bacteria from dividing and repairing. It does so stopping the action of a bacterial enzyme called DNA-gyrase. What if you forget to take Lumex?: If you miss a dose of Lumex, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Otitis media, Bacterial Conjunctivitis, Otitis externa Adult Dose: Ophthalmic Bacterial conjunctivitis Adults At the beginning of therapy on day 1: Instill 5 drops into the conjunctival sac within 20 minutes. Thereafter, until day 7-9: Instill 1 drop 3 times daily into the conjunctival sac. Otic/Aural Otitis externa 10 drops (0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear once daily for 7 days. Chronic Suppurative Otitis Media with perforated tympanic membranes: 10 drops (0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear twice daily for 14 days. Child Dose: Ophthalmic Bacterial conjunctivitis Adults At the beginning of therapy on day 1: Instill 5 drops into the conjunctival sac within 20 minutes. Thereafter, until day 7-9: Instill 1 drop 3 times daily into the conjunctival sac. Otic/Aural Otitis externa For patients 13 years and older: 10 drops (0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear once daily for 7 days. Acute Otitis Media (1 to 12 years old) with tympanostomy tubes is: 5 drops (0.25 mL, 0.75 mg ofloxacin) instilled into the affected ear twice daily for 10 days. Chronic Suppurative Otitis Media with perforated tympanic membranes: 12... Contraindication: Lomefloxacin is contraindicated in patients with a history of hypersensitivity to Lomefloxacin, quinolone or any other components of this product. Mode of Action: Lomefloxacin promotes breakage of double-stranded DNA in susceptible organisms and inhibits DNA gyrase, which is essential in reproduction of bacterial DNA. Precaution: Long term treatment with antibiotics may enhance development of secondary fungal infections or may support growth of non-susceptible bacteria. Contact lenses should not be worn in the presence of infectious eye diseases and the product should not be instilled while wearing contact lenses. During prolonged use, it is recommended that physicians conduct periodic examinations of the eye, including measurement of the intraocular pressure. Side Effect: Mild, transient sensation of burning, irritation or pain may be experienced on instillation. Interaction: Reduced bioavailability with sucralfate, antacids containing magnesium or aluminium, vitamin or mineral supplements containing iron. Increased serum levels with cimetidine. Potential increase in serum levels of ciclosporin. Renal elimination reduced with probenecid. Potentially Fatal: Increased risk of ventricular arrhythmias with class IA (quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmic agents.