Gavisol - Suspension Sodium Alginate + Sodium Bicarbonate + Calcium Carbonate - 500mg+267mg+160mg/10ml 1 200ml bot(s) / 200ml bot The Ibn Sina Pharmaceutical Ind. Ltd. Indication: Symptomatic relief of, upset stomach or dyspepsia, associated w/ hyperacidity. Alleviates the painful conditions resulting from gastric acid & bile reflux into oesophagus. Dyspepsia, associated w/, gastric reflux, reflux oesophagitis, heartburn, hiatus hernia, flatulence associated w/ gastric reflux, heartburn of pregnancy, regurgitation & in all cases of epigastric & retrosternal distress where the underlying cause is gastric reflux. Administration: Should be taken with food: Take after meals & at bedtime. Adult Dose: Suspension Adults: 10-20ml after meals and at bedtime, up to four times a day. Child Dose: Suspension Children over 12 years: 10-20ml after meals and at bedtime, up to four times a day. Contraindication: Hypersensitivity. Mode of Action: The mode of action of the product is physical and does not depend on absorption into the systemic circulation. On ingestion the product reacts rapidly with gastric acid to form a raft of Alginic acid gel having a near neutral pH and which floats on the stomach contents, quickly and effectively impeding gastro-esophageal reflux, for up to 4 hours. In severe cases the raft itself may be refluxed into the esophagus, in preference to the stomach contents, and exert a demulcent effect. Precaution: Na-restricted diet. Hypercalcaemia, nephrocalcinosis & recurrent Ca-containing renal calculi. Reduced efficacy w/ very low levels of gastric acid. Antacid use may mask symptoms of internal bleeding secondary to NSAIDs. Childn <12 yr. Side Effect: Allergic reactions like urticaria or bronchospasm, anaphylactic or anaphylactoid reactions. Ingestion of large quantities may cause alkalosis, hypercalcaemia, acid rebound, milk alkali, syndrome or constipation. Interaction: H2-antihistamines, tetracyclines, digoxin, fluoroquinolone, Fe salt, ketoconazole, neuroleptics, thyroxine, penicillamine, β-blockers, glucocorticoid, chloroquine, diphosphonates.