Fungimin - Cream Miconazole Nitrate 2% Topical - 2% 1 10gm tube(s) / 10gm tube Kumudini Pharma Ltd. Indication: Skin and nail infections due to dermatophytes, yeasts and other fungi such as:, Tinea capitis, corporis, manuum, pedis, barbae, cruris, unguium or onychomycosis, Pityriasis versicolor, candidiasis of skin and nails, stomatitis angularis, otitis externa, mycoses secondarily infected with bacteria. Adult Dose: Topical/Cutaneous Adult: Tinea cruris, corporis & cutaneous canidiasis: Apply to affected area BID for 2 weeks Tinea versicolor: Apply once daily to affected area for 2 weeks Tinea pedis: Apply BID to affected area for 4 weeks Child Dose: Tinea 2 years: Apply BID for up to 1 month Contraindication: History of sensitivity reactions to Miconazole or any of the components of the preparation. Mode of Action: Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients. Precaution: For external use only. Avoid introduction into the eyes. Lactation: not known whether distributed into milk; use caution Side Effect: Irritation,BurningmMaceration,Allergic contact dermatitis Irritation, burning, maceration, allergic contact dermatitis (all rare) Interaction: May increase anticoagulant effect of warfarin. May increase or prolong the effect of the following drugs: Oral hypoglycaemics (e.g. sulfonylureas), phenytoin, HIV protease inhibitors (e.g. saquinavir), antineoplastic agents (e.g. vinca alkaloids, busulfan, docetaxel), Ca channel blockers (e.g. dihydropyridines, verapamil), immunosuppressive agents (e.g. ciclosporin, tacrolimus, sirolimus), carbamazepine, cilostazol, buspirone, disopyramide, alfentanil, sildenafil, alprazolam, brotizolam, midazolam IV, rifabutin, methylprednisolone, trimetrexate, ebastine and reboxetine. Potentially Fatal: Increased risk of cardiac arrhythmia w/ astemizole, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole, terfenadine. May increase exposure to ergot alkaloids leading to ergotism. May increase the risk of rhabdomyolysis w/ HMG-CoA reductase inhibitors (e.g. simvastatin and...