Fluticon - Nasal Spray Fluticasone Propionate Nasal prep - 50mcg/spray 1 120 Metered Sprays(s) / 120 Metered Sprays The ACME Laboratories Ltd. Introduction: Fluticon is a steroid. It relieves the symptoms of allergic rhinitis such as runny nose, sneezing and sinus discomfort. It works by blocking the production of certain chemical messengers that cause inlammation (swelling) and allergies, thus relieving the discomfort and irritation in your nose. You should always use Fluticon as advised by your doctor. To get the full benefit of the medicine you should take it regularly. Normally, you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other and then sniff hard to make sure it reaches deep into the... Uses of Fluticon: Sneezing and runny nose due to allergies Side effects of Fluticon: Nasal irritation How to use Fluticon: Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils. How Fluticon works: Fluticon is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies. Indication: Seasonal and Perennial allergic and nonallergic, rhinitis, Nasal polyps Adult Dose: Nasal Allergic rhinitis Adults: 2 sprays(100mcg) in each nostril once a day, preferably in the morning. In some cases 2 sprays into each nostril twice daily, not exceeding 4 sprays. Nasal polyps Adult: 4 sprays (200 mcg) into each nostril 1-2 times daily for at least 4-6 wk. Child Dose: Nasal Allergic rhinitis Children over 12 years: 2 sprays(100mcg) in each nostril once a day, preferably in the morning. In some cases 2 sprays into each nostril twice daily, not exceeding 4 sprays. Children under 12 years (4 - 11 Years): 1 spray (50mcg) in each nostril once a day. The maximum total daily dosage should not exceed 4 sprays. Nasal polyps Child: >16 yr 4 sprays (200 mcg) into each nostril 1-2 times daily for at least 4-6 wk. Contraindication: Hypersensitivity. Mode of Action: Fluticasone utilises a fluorocarbothioate ester linkage at the C17 position. It has potent vasoconstrictive and anti-inflammatory activity, but weak HPA inhibitory effect when applied topically. Precaution: Rarely, immediate hypersensitivity reactions or contact dermatitis may occur after the administration of Fluticasone Propionate nasal spray. Rare instances of wheezing, nasal septum perforation, cataracts, glaucoma and increased intraocular pressure have been reported following the intranasal application of corticosteroids, including Fluticasone Propionate. Although systemic effects have been minimal with recommended doses of Fluticasone Propionate nasal spray, potential risk increases with larger doses. Therefore, larger than recommended doses of Fluticasone Propionate nasal spray should be avoided. Lactation: Unknown whether distributed in breast milk; caution advised Side Effect: >10% Headache (17%),URI (15%) 1-10% Nasal congestion (8%),Pharyngitis (6-8%),Asthma symptoms (3-7%),Fever (1-5%),Dysphonia (4%),Cough (3-4%),Nasal discharge (1-3%),Aches and pains (1-3%),Flu-like syndrome (1-3%),Bronchitis (1-3%),Diarrhea (1-3%),Abdominal pain (1-3%),Nasal ulcer (1%) Frequency Not Defined Loss of taste With the nasal spray, drying of the nose and an increase in the incidence of nosebleeds may occur. Potentially Fatal: Paradoxical bronchospasm. Pregnancy Category Note: Pregnancy Available data on inhaled or intranasal fluticasone propionate use in pregnant women have not reported a clear association with adverse developmental outcomes Fluticasone propionate crossed the placenta following subcutaneous administration to mice and rats and oral administration to rabbits Lactation There are no available data on fluticasone propionate in human milk, effects on breastfed child, or effects on milk production Developmental and health benefits of breastfeeding should be considered and adverse effects on breastfed child from treatment or from an underlying maternal condition Interaction: May lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors such as ritonavir.