Flumelone N - Eye Drop Fluormetholone + Neomycin Sulphate - 0.1% 1 5ml drop(s) / 5ml drop Reman Drug Laboratories Ltd. Introduction: Flumelone N is a prescription medicine having a combination of medicines that is used to treat bacterial infections. It stops the growth of bacteria and helps in relieving redness, itching and swelling. Flumelone N is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or... Uses of Flumelone N: Bacterial eye infections Side effects of Flumelone N: Eye irritationEye discomfort How to use Flumelone N: This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. How Flumelone N works: Flumelone N is a combination of two medicines: Neomycin and Fluorometholone. Neomycin is an antibiotic. It stops bacterial growth in the eye by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Fluorometholone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen and itchy. Indication: Allergic and inflammatory conditions of the eye Adult Dose: Adult: Instil 1-2 drops 2-4 times/day. May increase dose to 4 hrly in severe cases during the initial 24-48 hr. Contraindication: Viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), Vaccinia and Varicella, mycobacterial eye infection, ocular fungal infections, untreated eye infections; hypersensitivity. Mode of Action: Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation. Neomycin is an aminoglycoside antibiotic. It binds to 30S ribosomal subunits of bacterial ribosome thus inhibiting protein synthesis and generating errors in genetic code transcription causing cell death. It acts against many gram-negative aerobes and some gram-positive aerobes. It lacks activity against fungi, viruses and most anaerobic bacteria. Precaution: Glaucoma (check intraocular pressure periodically), history of herpes simplex fungal or bacterial infections. Not to be used in mustard gas keratitis and Sjogren's keratoconjunctivitis. May cause corneal and scleral thinning which may lead to perforation in serious cases. Use of steroids after cataract surgery may prolong healing time and increase bleb formation. Pregnancy, lactation; children <2 yr. Side Effect: Elevated intraocular pressure, optic nerve damage, postsubcapsular cataract formation, delayed wound healing, uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, loss of accommodation, secondary ocular infections, rarely systemic hypercorticoidism.