Flacol Pediatric Drop - Pediatric Drops Simethicone - 67mg/ml 1 15ml drop(s) / 15ml drop Square Pharmaceuticals PLC. Indication: Peptic ulcer, Infantile colic, Upper GI bloating, Functional dyspepsia, Spastic or irritable colon Administration: Should be taken after meals and at bedtime Adult Dose: Adults: 40 to 125 mg (0.6 to 1.9 ml drops) 4 times daily up to 500 mg/day (7.5 ml drops). OR 1-3 chewable tablets; 4 times daily, up to 500 mg/day (12 chewable tablets). Child Dose: Children older than 12 years of age: 40 to 80 mg (0.6 to 1.2 ml drops) 4 times daily up to 500 mg/day (7.5 ml drops). Children 2 to12 years of age: 40 mg (0.6 ml drops) 4 times daily. Children younger than 2 years of age: 20 mg (0.3 ml drops) 4 times daily up to 240 mg/day (3.6 ml drops). Contraindication: There is no information about the contraindication of Simethicone. Mode of Action: Changes surface tension of gas bubbles and causes collapse of foam bubbles, thus allowing easier passage of gas and preventing gas pockets in gastrointestinal tract. Precaution: More than 12 doses per day should not be used, except under the advice and supervision of a physician. Keep the medicine out of the reach of children. Side Effect: Simethicone is physiologically inert and no adverse effect has been reported after oral ingestion. Loose stools.