Famina Z - Capsule Carbonyl Iron + Folic acid + Vitamin B complex + Vitamin C + Zinc - 1 Capsule(s) / Capsule Silva Pharmaceuticals Ltd. Indication: Iron, Folic acid, Zinc, vitamins B and Vitamin C deficiency during pregnancy and lactation Administration: For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation Adult Dose: One capsule daily. In more severe cases, 2 capsules a day may be required. Contraindication: This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. Mode of Action: Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin. Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy. Zinc: Cofactor in over... Precaution: Care should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired. Lactation: Present in breast milk, use caution Side Effect: Generally well tolerated. However, a few allergic reactions may be seen. A few side-effects of oral iron preparations, including nausea, vomiting, constipation or diarrhoea may occur. Interaction: Carbonyl iron: Antacids may decrease the absorption of carbonyl iron. Folic acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations. Vit C: Deferroxamine, hormonal contraceptives, flufenazine, warfarin, elemental iron, salicylates, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.