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Econate VT - Tablet
Econazole Nitrate (Vaginal prep) - 150mg
3 Tablet(s) / Box
Incepta Pharmaceuticals Ltd.
Indication: Vaginal thrush, Vulvo-vaginal candidiasis, Fungal infection of vagina.
Adult Dose: Vag candidiasis As VT: 150 mg/day at bedtime for 3 consecutive nights. Vaginal infection As Vaginal cream: Applied with the applicator par vaginally once or twice daily.
Contraindication: Hypersensitivity. Porphyria;
Mode of Action: Econazole modifies the permeability of cell wall membrane in fungi; may interfere w/ RNA and protein synthesis, and lipid metabolism.
Precaution: Avoid contact with eyes and mucous membranes. May damage latex contraceptives. During pregnancy: There is no information of any abnormality or adverse event in neonates while Econazole Cream / VT had been used during pregnancy. During lactation: As the systemic absorption of Econazole Nitrate cream is extremely low after topical/vaginal use, excretion in breastmilk is likely to be negligible. So, it can be used topically/vaginally during lactation if needed.
Side Effect: Vulvar/vaginal burning; erythema; itching;
Interaction: Theoretical potential for compd metabolized by CYP3A4/2C9, oral anticoagulants eg warfarin & acenocoumarol.
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