Dilator 10 - Tablet Bambuterol Hydrochloride - 10mg 10 Tablet(s) / Strip Eskayef Pharmaceuticals Ltd. Introduction: Dilator 10 is used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD) such as coughing, wheezing and breathlessness. It helps in relaxing the muscles of the air passages, thus widening it and making it easier to breathe. You can take Dilator 10 with or without food. The dose will depend on your condition and how your respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. Use this medicine regularly to get the most benefit from it even... Uses of Dilator 10: AsthmaChronic obstructive pulmonary disease (COPD) Side effects of Dilator 10: Insomnia (difficulty in sleeping)HeadachePalpitationsRestlessnessMuscle crampTrembling How to use Dilator 10: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dilator 10 may be taken with or without food, but it is better to take it at a fixed time. How Dilator 10 works: Dilator 10 is a bronchodilator. It works by relaxing the muscles in the airways and widens airways. This makes breathing easier. Indication: Chronic obstructive pulmonary disease (COPD), Asthma. Adult Dose: Adult: PO 10-20 mg/day at bedtime. Hepatic impairment: Severe: Not recommended. Renal Dose: Renal impairment: CrCl (ml/min) <50 Initial dose should be halved. Contraindication: Severe hepatic impairment; cirrhosis. Mode of Action: Bambuterol HCl is a prodrug of terbutaline. It relaxes bronchial smooth muscle by selectively acting on ?2-receptors. Precaution: DM, hyperthyroidism, myocardial insufficiency, arrhythmias, susceptibility to QT-interval prolongation. Pregnancy. Side Effect: Fine tremor of skeletal muscle (e.g. hands), palpitations and muscle cramps; tachycardia, tenseness and peripheral vasodilation. Interaction: Risk of hypokalaemia increased by co-admin of corticosteroids, diuretics or xanthines. Prolong the action of drugs e.g. suxamethonium.