Daclin Lotion - Lotion Clindamycin 1% Topical - 10mg/ml 1 25ml bot(s) / 25ml bot ACI Limited Introduction: Daclin Lotion is an antibiotic that fights bacteria. It is used to treat acne, which appears as spots or pimples on your face, chest or back. This medicine works by attacking the bacteria that cause these pimples. Daclin Lotion is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. It should not be applied to broken or damaged skin. Avoid any contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get it... Side effects of Daclin Lotion: Skin rash How to use Daclin Lotion: Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. How Daclin Lotion works: Daclin Lotion is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing, and prevents the infection from spreading. What if you forget to take Daclin Lotion?: If you miss a dose of Daclin Lotion, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Acne vulgaris, erythrasma, rosacea, periorificial dermatitis, folliculitis, stasis, chronic lymphaedema and familial pemphigus, dermal ulcers. Adult Dose: Topical/Cutaneous Acne Adult: As 1% preparation: Apply a thin layer onto affected area bid. Child Dose: 12 years: Apply a thin layer onto affected area bid. Contraindication: Contraindicated in patients with hypersensitivity to clindamycin. Mode of Action: Clindamycin inhibits protein synthesis by reversibly binding to the 50S subunit of the ribosomal thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting to stunted cell growth. Precaution: It is not for oral, ophthalmic, or Intravaginal use. Avoid exposure to sunlight and sunlamps. Wear sunscreen daily. Lactation: Excretion in milk unknown; use with caution Side Effect: >10% Dryness (18-23%),Oiliness (1-18%),Erythema (7-16%),Peeling (7-11%),Burning/itching (6-11%) 1-10% Headache (3%) Pregnancy Category Note: Pregnancy In clinical trials with pregnant women, systemic administration of clindamycin during second and third trimesters has not been associated with increased frequency of congenital abnormalities; there are no adequate studies in pregnant women during first trimester of pregnancy; clindamycin should be used during first trimester of pregnancy only if clearly needed Lactation Not known whether clindamycin is excreted in human milk following therapy; however, orally and parenterally administered clindamycin has been reported to appear in breast milk; clindamycin has potential to cause adverse effects on breastfed infant's gastrointestinal flora; if oral or intravenous clindamycin is required by a nursing... Interaction: May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding w/ vit K antagonists (e.g. warfarin, acenocoumarol, fluindione).