CodLiver Oil - Capsule Cod Liver Oil (Vitamin A + D) - 85IU 15 Capsule(s) / Strip Drug International Ltd. Indication: Nutritional supplements, Vitamin A , D & E deficiency, Osteoarthritis, Glaucoma, Hypertension, Depression, Multiple sclerosis, Pain and joint stiffness, Kidney disease, High triglycerides, Heart disease, Systemic lupus erythematosus (SLE), Middle ear infections (otitis media). Adult Dose: Adult: 1-2 capsule 3 times daily with meals. Child Dose: Child over 6 years: 1-2 capsule 3 times daily with meals. Contraindication: Hypersensitivity. Mode of Action: Vitamin A plays an essential role in the function of retina and is essential for growh and differentiation of epithelial tissue. Vitamin D is supplemented for prevention and cure of nutritional and metabolic rickets and for treatment of hypoparathyroidism. Vitamin E is an antioxidant which preserves essential cellular constituents. Vitamin E plays a role in protecting red blood cells against hemolysis; has protective effects against free radicals on polyunsaturated fatty acids found in cell membranes; plays a role in preventing oxidation of vitamin A and C. Precaution: Chronic renal failure, Patients having hepatomegaly & raised ESR Side Effect: Hypervitaminosis;hypercalcemia, myopathy; thrombophloebitis; fatigue, weakness, nausea, headache, dizziness, blurred vision, flatulence, diarrhoea, abdominal pain. Interaction: Colestyramine, colestipol, and orlistat may interfere with vitamin E absorption. High doses of vitamin E potentiates the anticoagulant action of warfarin. Large doses of vitamin E may impair response to iron supplementation.