Cefditor 200 - Tablet Cefditoren - 200mg 4 Tablet(s) / Strip Orion Pharma Ltd. Introduction: Cefditor 200 is an antibiotic medicine used to treat a variety of bacterial infections. It is effective in infections of the respiratory tract (eg. pneumonia), urinary tract, ear, nasal sinus, throat, and some sexually transmitted diseases. Cefditor 200 should be taken with food to avoid an upset stomach. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course... Uses of Zostum-O Tablet: Bacterial infections Side effects of Zostum-O Tablet: NauseaIndigestionStomach painDiarrhea How to use Zostum-O Tablet: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cefditor 200 is to be taken with food. How Zostum-O Tablet works: Cefditor 200 is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive. What if you forget to take Zostum-O Tablet?: If you miss a dose of Cefditor 200, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Pharyngitis, Community-acquired pneumonia, Susceptible infections, Tonsillitis, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitis Administration: Should be taken with food. Adult Dose: Oral Community-acquired pneumonia Adult: 400 mg bid for 14 days. Acute bacterial exacerbation of chronic bronchitis Adult: 400 mg bid for 10 days. Pharyngitis ; Tonsillitis; Uncomplicated skin and skin structure infections Adult: 200 mg bid for 10 days. Child Dose: 12 years old: As in adults Renal Dose: Renal impairment: CrCl (ml/min) 30-49 Maximum: 200 mg bid <30 Maximum: 200 mg once daily Contraindication: Hypersensitivity to Cefditoren, other cephalosporins; or milk proteins. Carnitine deficiency. Mode of Action: Cefditoren is a third generation cephalosporin used for treatment of susceptible infections caused by gram-positive and gram-negative bacteria. It inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs). Precaution: Pregnancy and lactation. Patients with penicillin allergy. Avoid prolonged use as pivalate-containing compounds may cause carnitine deficiency over time; greater risk of carnitine deficiency in patients with renal impairment or decreased muscle mass. May decrease prothrombin activity especially in patients with renal or hepatic impairment, poor nutritional status, prolonged antibiotic treatment or patients previously stabilised on anticoagulant therapy. Long term use may result in development of drug-resistant bacteria, or superinfection including Clostridium difficile-associated diarrhoea and pseudomembranous colitis. Lactation: excretion in milk unknown; use with caution Side Effect: >10% Diarrhea (11-15%) 1-10% Nausea (4-6%),Headache (2-3%),Abdominal pain (2%),Dyspepsia (1-2%),Vomiting (1%) <1% Bacterial/fungal superinfection,C. difficile colitis,Hypersensitivity,Increased bleeding time,Stevens-Johnson syndrome,Vaginal moniliasis Potentially Fatal: Hypersensitivity, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis. Pregnancy Category Note: Pregnancy Category: B Lactation: excretion in milk unknown; use with caution Interaction: Reduced oral bioavailability when coadministered with antacids or H2-receptor antagonists. Probenecid may increase plasma concentration and prolong half-life of Cefditoren. May enhance anticoagulant effect of vitamin K antagonists (e.g. warfarin).