Cavinton 5 - Tablet Vinpocetine - 5mg 25 Tablet(s) / Strip City Overseas Introduction: Cavinton 5 is a prescription medicine used in the treatment of Alzheimer's disease, stroke and memory loss in Parkinson's disease. It can also be used to treat age related memory loss and head injury. It helps in the improvement of brain function and provides enhancement of focus. Cavinton 5 may be taken with or without food, preferably at the same time each day. Take it as advised by your doctor and if you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better.... Uses of Cavinton 5: Alzheimer's diseaseStrokeDementia in Parkinson's diseaseAge related memory lossHead injury Side effects of Cavinton 5: DizzinessDryness in mouthFlushing (sense of warmth in the face, ears, neck and trunk)HeadacheInsomnia (difficulty in sleeping)NauseaStomach painNervousness How to use Cavinton 5: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cavinton 5 may be taken with or without food, but it is better to take it at a fixed time. How Cavinton 5 works: Cavinton 5 is semisynthetic alkaloid. It has a nootropic (protects nerves and the brain) effect. It inhibits the voltage-dependent neuronal sodium channels, which in turn enhances a chemical messenger (intracellular cGMP levels) in the brain. Thus, increases blood flow within the brain. This is how it prevents the destruction of never cells (neurons) and protects the brain. Thus, helps enhancement of the nervous system. It also has an antioxidant property. This works by oxidizing the free radicals (toxins) in the body. Indication: Dementia, Cerebrovascular disorders, Stroke Administration: Should be taken with food. Take after meals. Adult Dose: Oral Adult Tablet: 1-2 tablets thrice daily, the maintenance dose is 1 tablet thrice daily. Parenteral IM Injection: Daily dose of 20-40 mg are to be given until improvement of symptoms is reached (for not longer than 10 days) then oral treatment should be applied. If this regimen fails, infusion treatment should be started. IV Infusion: The daily starting dose is 20 mg in slow drip infusion (2 ampoules in 500-1000 ml infusion solution). This dose can be increased to 1 mg/kg body weight during 3 to 4 days. Treatment should be continued for 10-14 days depending on the tolerance... Contraindication: Parenteral treatment- Severe ischaemic heart disease, severe rhythm disorders and pregnancy. Pregnancy, Lactation. Mode of Action: Vinpocetine is derived from vincamine. It increases cerebral circulation and utilisation of oxygen and is used in a variety of cerebral disorders. Shown to inhibit cGMP phosphodiesterase that has may result in increased cerebral blood flow. Reported to have calcium-channel blocker, voltage-gated sodium channel blocker, & acetylcholine release activities. Precaution: Hypertension or cardiac dysfunction. In the acute stage until the improvement of symptoms parenteral treatment is recommended followed by oral treatment. In chronic cases oral therapy should be applied. Side Effect: Transient hypotension, tachycardia. Interaction: Possible decrease in anticoagulation effect with warfarin.