Carva 75 - Tablet Aspirin - 75mg 15 Tablet(s) / Strip Square Pharmaceuticals PLC. Introduction: Carva 75 is an antiplatelet medicine used to treat and prevent heart attacks, strokes and heart-related chest pain (angina). It helps to prevent the formation of blood clots in your blood vessels. It is a very widely used medicine for heart protection. Carva 75 is usually best taken with food otherwise it may upset your stomach. The dose that is right for you depends on what you are taking it for and how well it helps your symptoms. You should take it as recommended by your doctor. The most common side effects of this medicine are heartburn or upset stomach,... Uses of Carva 75: Heart attackStrokeAngina (heart-related chest pain) Side effects of Carva 75: HeartburnIncreased bleeding tendencyNauseaUpset stomachVomiting How to use Carva 75: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Carva 75 is to be taken with food. How Carva 75 works: Carva 75 is a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action. It works by preventing platelets from sticking together which decreases the formation of harmful blood clots. This lowers the chance of heart attack or stroke. Indication: PO Prophylaxis of myocardial infarction Adult: 75-300 mg once daily. Lower doses should be used in patients receiving ACE inhibitors. Stent implantation Adult: 300 mg 2 hr before procedure followed by 150-300 mg/day thereafter. Mild to moderate pain and fever Adult: 150-300 mg repeated every 4-6 hr according to response. Max: 4 g/day. Pain and inflammation associated with musculoskeletal and joint disorders Adult: Initial: 2.4-3.6 g/day in divided doses. Usual maintenance: 3.6-5.4 g/day. Monitor serum concentrations. Hepatic impairment: Severe liver disease: Not recommended Administration: Alcohol, corticosteroids, analgin, phenylbutazone and oxyphenbutazone may increase risk of GI ulceration. Aspirin increases phenytoin levels. May antagonize actions of uricosurics and spironolactone. Potentially Fatal: May potentiate effects of anticoagulants, methotrexate and oral hypoglycaemics. Adult Dose: Patients with history of asthma, angioedema, urticaria or rhinitis, nasal polyp, severe renal or hepatic impairment, lactation. Lactation: Drug enters breast milk; decision should be made regarding whether to discontinue nursing or to discontinue drug, taking into account importance of drug to mother. Child Dose: Pregnancy category: C; D in 3rd trimester Renal Dose: Aspirin is an analgesic, anti-inflammatory and antipyretic. It inhibits cyclooxygenase, which is responsible for the synthesis of prostaglandin and thromboxane. It also inhibits platelet aggregation. Contraindication: PO Juvenile rheumatoid arthritis Child: 25 kg: 2.4-3.6 g/day Pain & Fever <12 years 10-15 mg/kg PO q4hr, up to 60-80 mg/kg/day Mode of Action: Should be taken with food. Precaution: Fever, Headache, Pain/inflammation, Acute coronary syndrome, TIA, MI, Stroke Side Effect: Renal impairment CrCl >10 mL/min: Dose adjustment not necessary CrCl <10 mL/min: Not recommended Pregnancy Category Note: GI disturbances; prolonged bleeding time, rhinitis, urticaria and epigastric discomfort; angioedema, salicylism, tinnitus; bronchospasm. Potentially Fatal: Gastric erosion, ulceration and bleeding; severe, occasionally fatal exacerbation of airway obstruction in asthma; Reye's syndrome (children <12 yr). Hepatotoxicity; CNS depression which may lead to coma; CV collapse and resp failure; paroxysmal bronchospasm and dyspnoea. Interaction: Hypersensitivity (attacks of asthma, angioedema, urticaria or rhinitis), active peptic ulceration; pregnancy (3rd trimester), children <12 yr, patients with haemophilia or haemorrhagic disorders, gout, severe renal or hepatic impairment, lactation.