Butalin - Syrup Salbutamol - 2mg/5ml 1 60ml bot(s) / 60ml bot United Chemicals & Pharmaceuticals Ltd. Introduction: Butalin belongs to a group of medicines called fast-acting bronchodilators or “relievers”. It’s used to treat the symptoms of asthma and chronic obstructive pulmonary disease (COPD) such as coughing, wheezing and feeling short of breath. You can take Butalin with or without food. The dose will depend on your condition and how your respond to the medicine. Try to take it at the same time each day. It's important to keep taking this medicine until your doctor tells you not to. Use this medicine regularly to get the most benefit from it even if you feel well. Butalin is generally... Uses of Butalin: AsthmaChronic obstructive pulmonary disease (COPD) Side effects of Butalin: HeadacheTremorMuscle cramp How to use Butalin: Check the label for directions before use. Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out. How Butalin works: Butalin is a bronchodilator. It works by relaxing the muscles in the airways and widens airways. This makes breathing easier. What if you forget to take Butalin?: If you miss a dose of Butalin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Acute severe asthma, Severe bronchospasm Administration: Tablet/Syrup: Should be taken on an empty stomach. Take 1 hr before or 2 hr after meals. Aerosol Metered-Dose Inhaler Prime the inhaler before using for the first time and in cases where the inhaler has not been used for >2 weeks by releasing 4 “test sprays” into the air, away from the face Patient instructions for administration Shake well before each use Breathe out fully through the mouth, expelling as much air from your lungs as possible; place the mouthpiece fully into the mouth, holding the inhaler in its upright position and close the lips around it While breathing... Adult Dose: Oral Acute bronchospasm Adult: 2-4 mg 3 or 4 times daily, up to 8 mg 3 or 4 times daily. As modified-release tab: 8 mg bid. Not to exceed 32 mg/day Elderly: 2 mg 3 or 4 times daily. Inhalation Acute bronchospasm, Intermittent episodes of asthma Adult: As metered-dose aerosol or dry powd inhaler (90 or 100 mcg/actuation): 1 or 2 inhalations (1 ConviCap) as a single dose when required. Not to exceed 12 inhalations/24 hr Chronic maintenance or prophylactic therapy Adult: As metered-dose aerosol or dry powd inhaler (90 or 100 mcg/actuation): 2 inhalations (1 ConviCap) 3-4 times daily.... Child Dose: Oral Children Acute bronchospasm Tablet Child: 2-6 yr 1-2 mg; >6-12 yr 2 mg; >12 yr 2-4 mg 3 or 4 times daily, up to 8 mg 3 or 4 times daily. Syrup 2 - 6 years: 2.5 ml syrup, 3-4 times daily 6-12 years: 5 ml syrup, 3-4 times daily Over 12 years: 5-10 ml syrup, 3-4 times daily (2-4 mg tablet, 3-4 times daily) Inhalation Acute bronchospasm Child: 4-12 yr 1 inhalationas a single dose, may be increased to 2 inhalations as necessary. Max: 400 mcg daily. Prophylaxis of exercise-induced bronchospasm Child: 4-12 yr 1 inhalation 10-15 min... Contraindication: Salbuatmol inhaler is contraindicated in patients with a history of hypersensitivity to any of its components. Although intravenous Salbutamol, and occasionally Salbutamol tablets, is used in the management of premature labour uncomplicated by conditions such as placenta praevia, ante-partum haemorrhage or toxaemia of pregnancy, Salbutamol inhaler preparations are not appropriate for managing premature labour. Salbutamol preparation should not be used for threatened abortion during the first or second trimesters of pregnancy. Mode of Action: Salbutamol is a direct-acting sympathomimetic with beta-adrenergic activity and selective action on ?2 receptors, producing bronchodilating effects. It also decreases uterine contractility. Precaution: Hyperthyroidism, myocardial insufficiency, arrhythmias, susceptibility to QT-interval prolongation, HTN, DM, glaucoma, hypokalaemia, seizure disorder. Renal impairment. Elderly. Pregnancy and lactation. Monitoring Parameters Monitor BP, heart rate, electrolyte and fluid balance; glucose, lactate and K levels. Lactation: Unknown whether drug is excreted in milk; not recommended Side Effect: >10% Tremor (20%),Nervousness in children aged 2-6 years (20%),Insomnia in children aged 6-12 years receiving 4-12 mg q12hr (11%) 1-10% Nausea (10%),Fever (1.6-9%),Bronchospasm (8%),Vomiting (7%),Headache (4-7%),Dizziness (1-7%),Cough (5%),Allergic reactions (4%),Otitis media (3.3%),Epistaxis in children (3%),Increased appetite (3%),Urinary tract infection (3%),Dry mouth (1%),Flu syndrome,Nervousness <1% Epigastric pain,Epistaxis in adults,Hyperactivity in children Frequency Not Defined Adverse reactions such as hypertension, angina, vertigo, central nervous system stimulation, insomnia, headache, metabolic acidosis, and drying or irritation of oropharynx Hypersensitivity,Hypokalemia,Increased blood glucose levels,Prolonged QT interval and ST-segment depression,Sleeplessness,Tachycardia (incidence varies with formulation) Urticaria, angioedema, rash, bronchospasm, and oropharyngeal edema (rare) Potentially Fatal: Potentially serious hypokalaemia... Interaction: Diuretics, corticosteroids and xanthines may augment hypokalaemia. CV effects potentiated by MAOIs, TCAs, sympathomimetics. Increases absorption of sulfamethoxazole when used together. May markedly increase heart rate and BP when used with atomoxetine. Reduces serum levels of digoxin. Hypokalaemia induced by salbutamol increases the risk of digitalis toxicity. BP should be closely monitored if linezolid is used concurrently with salbutamol.