Besone N - Ointment Betamethasone 0.1% + Neomycin Sulphate 0.5% Topical - 0.1%+0.5% 1 5gm tube(s) / 5gm tube Pharmadesh Laboratories Ltd. Introduction of Betamethasone: Besone N is a combination medicine that is used to treat various types of skin infections. It minimizes symptoms of inflammation such as redness, swelling, and itching. It also has an antimicrobial action against the infection-causing microorganisms. Besone N is for external use only. Use it in the dose and duration as advised by the doctor. Do not apply it on an open wound and avoid getting it into your eyes or mouth. In case of accidental contact, rinse it with plenty of water. Use it regularly to get the most benefit of the medicine. Using $may cause few side... Introduction of Neomycin: Besone N is a combination medicine that is used to treat various types of skin infections. It minimizes symptoms of inflammation such as redness, swelling, and itching. It also has an antimicrobial action against the infection-causing microorganisms. Besone N is meant for external use only. It should be applied only to the affected area of the skin as per the dosage and schedule prescribed by your doctor. In order to get the most benefit, apply it regularly and preferably at a fixed time each day. Do not use larger amounts or apply it more often or for a longer duration... Uses of Besone N: Allergic conditions Uses of Besone N: Bacterial infections Side effects of Besone N: Thinning of skinIncreased risk of infectionWeight gainMood changesBehavioural changes Side effects of Besone N: Application site reactions (burning, irritation, itching and redness) How Besone N works: Besone N is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies. How Besone N works: Besone N is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Indication: Lichen planus, Psoriasis, Eczema, Contact dermatitis, Seborrhoeic dermatitis, Systemic lupus erythematosus, Lichen simplex, Prurigo nodularis Adult Dose: Adult: Topical Apply 2-3 times/day. Usual duration: Up to 7 days/course. Child Dose: Child: >2 yr: As cream/ointment: Apply onto the affected area(s) 2-3 times daily. Usual treatment duration: Up to 5 days/course. Renal Dose: Renal impairment: Dose reduction may be necessary. Contraindication: Hypersensitivity. Rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus and primary cutaneous viral infections. Not to be used in otitis externa complicated by ear-drum perforation. Treatment of primary infected skin lesions caused by fungi or bacteria; primary or secondary infections due to yeast; or secondary infections due to Pseudomonas or Proteus species. Mode of Action: Betamethasone valerate is a corticosteroid which is effective in inflammatory dermatoses. It is also effective in less responsive conditions such as psoriasis. Neomycin sulfate is a broad spectrum antibiotic. It is bactericidal against many bacteria which are commonly associated with skin infections. Precaution: Avoid prolonged treatment as it may lead to systemic corticosteroid effects even withour occlusion. Avoid prolonged excessive application to the facial areas. Withdraw treatment if there is spread of the infection. Risk of glaucoma development if preparation enters eye(s). Regular monitoring is recommended when used in psoriasis due to treatment tolerance, rebound relapses, generalised pustular psoriasis or systemic toxicity. Increased risk of contact sensitisation when used for extended period or recurrently. Pregnancy and lactation. Side Effect: Prolonged use may cause local atrophic changes in the skin e.g. thining, striae and dilatation of superficial blood vessels. Local skin burning sensation, pruritus, pigmentation changes, allergic contact dermatitis and hypertrichosis. Ophthalmic preparation: Corneal ulceration, increased intraocular pressure, mydriasis, ptosis, epithelial punctate keratitis. Interaction: If there is significant systemic absorption, neomycin sulfate may increase the respiratory depressant effects of neuromuscular blockers.