Benylin Mucus Cough & Cold All In One Relief - Tablet Paracetamol + Phenylephrine + Guaifenesin - 250mg+100mg+5mg 16 Tablet(s) / Box Benylin Indication: Temporary Relief of Sinus Congestion, Headache, Minor Aches & Pains Adult Dose: Temporary Relief of Sinus Congestion, Headache, Minor Aches & Pains 2 tabs PO q4hr; not to exceed 12 tabs/24hr; not to exceed 1g/hr or 4g/day of Paracetamol 30 mL [(325mg/5mg/200mg)/15mL] PO q4hr 20 mL [(162.5mg/5mg/2.5mg/100mg)/5mL] PO q4hr Child Dose: >12 years 2 tabs PO q4hr; not to exceed 12 tabs/24hr; not to exceed 1g/hr or 4g/day of Paracetamol 30 mL [(325mg/5mg/200mg)/15mL] PO q4hr 20 mL [(162.5mg/5mg/2.5mg/100mg)/5mL] PO q4hr Contraindication: Hypersensitivity G-6-PD deficiency Severe hepatotoxicity Mode of Action: Paracetamol blocks pain impulse generation peripherally & may inhibit the generation of prostaglandin in the CNS; reduces fever by inhibiting the hypothalamic heat-regulating center Phenylephrine is a vasoconstrictor and decongestant that relieves symptoms resulting from irritation of upper respiratory tract tissue; shrinks swollen mucous membranes, reduces nasal congestion and tissue hyperemia Guaifenesin increases respiratory tract fluid secretions and helps to loosen phlegm and bronchial secretions. Precaution: Phenylephrine: Caution in elderly patients, hyperthyroidism, myocardial disease, bradycardia, partial heart block or severe arteriosclerosis Paracetamol: Hepatotoxicity possible in chronic alcoholics following various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; contained in many OTC products and combined use with these products may result in toxicity due to cumulative doses exceeding recommended maximum dose Paracetamol: Risk for rare, but serious skin reactions that can be fatal; these reactions include Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP); symptoms may include skin redness, blisters and rash Guaifenesin: not... Side Effect: Frequency Not Defined Hypertension Severe peripheral and visceral vasoconstriction Tachycardia Dizziness Drowsiness Excitability Headache Restlessness Tremor Dermatologic rash Nausea Vomiting Anemia blood dyscrasias (neutropenia, pancytopenia, leukopenia) Bilirubin and alkaline phosphatase may increase