Avaflut Nasal Spray - nasal_spray Fluticasone Furoate Nasal prep - 27.5mcg/Spray 1 120 Metered Sprays(s) / 120 Metered Sprays OSL Pharma Limited Introduction: Avaflut Nasal Spray is a steroid. It relieves the symptoms of allergic rhinitis such as runny nose, sneezing and sinus discomfort. It works by blocking the production of certain chemical messengers that cause inflammation (swelling) and allergies, thus relieving the discomfort and irritation in your nose. You should always use it as advised by your doctor but to get the full benefit you should take it regularly. It may take a few days for the spray to take full effect. If you do not see an improvement in your symptoms after a week you should talk to your doctor. The... Uses of Avaflut Nasal Spray: Sneezing and runny nose due to allergies Side effects of Avaflut Nasal Spray: NosebleedsHeadacheNasal inflammation How to use Avaflut Nasal Spray: Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils. How Avaflut Nasal Spray works: Avaflut Nasal Spray is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies. Indication: Allergic rhinitis Adult Dose: Nasal Allergic rhinitis Adult: As fluticasone furoate spray: 2 sprays (55 mcg) into each nostril once daily, may reduce to 1 spray (27.5 mcg) into each nostril once daily if symptoms are controlled. Child Dose: Nasal Allergic rhinitis (Seasonal/Perennial) Child: 2-11 yr: 1 spray in each nostril once a day, may be increased to 2 sprays (55 mcg) into each nostril once daily if necessary. Contraindication: Fluticasone Furoate nasal spray is contraindicated in patients with a hypersensitivity to any of its ingredients. Mode of Action: Fluticasone Furoate is a synthetic, trifluorinated corticosteroid that provides anti-inflammatory activity. It binds to glucocorticoid receptor and inhibits the migration of inflammatory mediator & cells (histamine, leukotrienes, mast cells, eosinophils etc) Precaution: Rarely, immediate hypersensitivity reactions or contact dermatitis may occur after the administration of Fluticasone Furoate nasal spray. Rare instances of wheezing, nasal septum perforation, cataracts, glaucoma and increased intraocular pressure have been reported following the intranasal application of corticosteroids, including Fluticasone Furoate. Although systemic effects have been minimal with recommended doses of Fluticasone Furoate nasal spray, potential risk increases with larger doses. Therefore, larger than recommended doses of Fluticasone Furoate nasal spray should be avoided. Lactation: Unknown whether distributed in breast milk; caution advised Side Effect: >10% Headache (17%),URI (15%) 1-10% Nasal congestion (8%),Pharyngitis (6-8%),Asthma symptoms (3-7%),Fever (1-5%),Dysphonia (4%),Cough (3-4%),Nasal discharge (1-3%),Aches and pains (1-3%),Flu-like syndrome (1-3%),Bronchitis (1-3%),Diarrhea (1-3%),Abdominal pain (1-3%),Nasal ulcer (1%) Frequency Not Defined Loss of taste Potentially Fatal: Paradoxical bronchospasm. Pregnancy Category Note: Pregnancy Available data on inhaled or intranasal fluticasone propionate use in pregnant women have not reported a clear association with adverse developmental outcomes Fluticasone propionate crossed the placenta following subcutaneous administration to mice and rats and oral administration to rabbits Lactation There are no available data on fluticasone propionate in human milk, effects on breastfed child, or effects on milk production Developmental and health benefits of breastfeeding should be considered and adverse effects on breastfed child from treatment or from an underlying maternal condition Interaction: May lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors such as ritonavir.