Androgel 16.2mg - Gel Testosterone 1% Topical - 88gm 1 88gm tube(s) / 88gm tube Dermolive Introduction: Androgel 16.2mg is a medicine used in the treatment of male hypogonadism caused due to low testosterone levels. It is only prescribed to the men with known medical conditions. It helps in restoring the level of testosterone in the male body. Androgel 16.2mg is injected directly into the skin or muscles under the medical supervision of a doctor. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for... Uses of Androgel 16.2mg: Male hypogonadism Side effects of Androgel 16.2mg: Injection site reactions (pain, swelling, redness)Absence of menstrual periodsTirednessJoint painBack pain How to use Androgel 16.2mg: Your doctor or nurse will give you this medicine. Kindly do not self administer. How Androgel 16.2mg works: Androgel 16.2mg is similar to the natural male hormone, testosterone. It works by replenishing the deficient testosterone levels in adult men. Lack of testosterone may cause various health problems including impotence, infertility, low sex drive, tiredness, depressive mood and bone loss. Indication: Hypogonadism, Testosterone replacement therapy Administration: Applying the gel to skin of lower abdomen, inner thighs or shoulders and upper arms, usually once daily. Adult Dose: Topical Adult: Testosterone gels: 50 mg/day initially, applied topically to shoulders, upper arms, or abdomen (not to genitals) each morning; titrated according to predose serum testosterone levels (25 mg/2.5 g, 50 mg/5 g); not to exceed 100 mg/day Child Dose: Safety and efficacy not established Contraindication: Hypercalcaemia or hypercalciuria, males with breast or prostate carcinoma. Pregnancy and lactation. Mode of Action: Testosterone is the principal endogenous androgen responsible for promoting the growth and development of male sexual organs and maintaining secondary sex characteristics in androgen-deficient males. Precaution: Cardiovascular disorders, skeletal metastases, renal or hepatic impairment, epilepsy, migraine, diabetes or other conditions which may be aggravated by fluid retention, eg heart failure. Elderly, prepubertal boys. Monitor signs of virilization (females) and development of priapism or excessive sexual stimulation (males). Periodic haemoglobin, lipid determinations and rectal prostate examination. Lactation: Drug is excreted into breast milk; use is contraindicated Side Effect: >10% Pruritus at application site (37%),Skin reactions at application site (16.1%),Blisters under skin (12%) 1-10% Erythema at application site (7%),Vesicles at application site (6%),Allergic contact dermatitis (4%),Burning at application site (3%),Induration at application site (3%) Frequency Not Defined Abnormal dreams,Acne,Anaphylaxis,Bladder irritability,Breast soreness,Cholestatic jaundice,Deep vein thrombosis, Dry skin,Fatigue,Gynecomastia,Headache,Insomnia,Menstrual irregularities,Priapism,Suppression of factors II, V, VII,Virilization Interaction: Enhance activities of ciclosporine, antidiabetics, thyroxine, anticoagulants. Long term use of testosterone may cause resistance to effects of neuromuscular blockers. Enhance fluid retention from corticosteroids.