Anasone - Tablet Dapsone - 100mg 30 Tablet(s) / Box Non Brand Introduction: Anasone belongs to a class of drugs known as anti-leprotic medicines. It is used to treat leprosy and acne. It works by stopping the growth of disease causing organisms in the body. It also helps to reduce redness and swelling associated with acne (commonly known as pimples). Anasone should be used in the dose and duration as advised by your doctor. It should be taken with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for... Uses of Anasone: Leprosy Side effects of Anasone: RashFever How to use Anasone: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Anasone may be taken with or without food, but it is better to take it at a fixed time. How Anasone works: Anasone is an anti-leprotic medication. It works by stopping the production of folic acid in certain bacteria, thereby stopping them from growing. Indication: Pneumonia, Acne, Leprosy, Dermatitis herpetiformis Adult Dose: Dermatitis Herpetiformis 50 mg PO qDay, titrate to 300 mg qDay or higher to achieve desired effect Reduce dose to minimum effective dose within the range of 50-300 mg qDay as soon as possible Leprosy 100 mg PO qDay, in combination with other antileprosy drugs Tuberculoid or Lepromatous Disease 100 mg PO qDay with rifampin 600 mg PO qDay Child Dose: Child: PO 2 mg/kg, max 100 mg q24h 4 mg/kg, max 200 mg Once weekly Contraindication: Hypersensitivity. Severe anaemia, porphyria. Mode of Action: Dapsone inhibits folic acid synthesis by preventing normal bacterial utilization of PABA (PABA). Precaution: G6PD deficiency, methaemoglobin or Hb M. Perform regular blood counts and monitor liver function regularly. Pregnancy and lactation. Lactation: Enters breast milk; not recommended (AAP Committee states "compatible with nursing") Side Effect: 1-10% Hemolysis,Methemoglobinemia <1% Reactional states (ie, abrupt changes in clinical activity occurring during any leprosy treatment; classified as reversal of erythema nodosum leprosum reactions),Insomnia,Headache,Exfoliative dermatitis,Photosensitivity,Nausea,Vomiting,Anemia,Leukopenia,Agranulocytosis,Hepatitis,Cholestatic jaundice,Peripheral neuropathy (usually in nonleprosy patients),Blurred vision,Tinnitus,SLE Potentially Fatal: Agranulocytosis, serious cutaneous hypersensitivity reactions, exfoliative dermatitis. Pregnancy Category Note: Pregnancy category: C Lactation: Enters breast milk; not recommended (AAP Committee states "compatible with nursing") Interaction: Decreased serum conc of dapsone when used with rifampicin. Increased plasma conc with probenecid, trimethoprim. Antagonize clofazimine.