Alestin - Syrup Ebastine - 5mg/5ml 1 50ml bot(s) / 50ml bot Novelta Bestway Pharmaceuticals Ltd. Introduction: Alestin belongs to a group of medicines called antihistamines. It is used in the treatment of various allergic conditions. It relieves symptoms like itching, swelling and rashes. Alestin may be taken with or without food. The dose may vary depending on what you are taking it for. Take it as it has been prescribed by your doctor. You may need this medicine only on days you have symptoms, or you may need to take it every day to prevent symptoms from happening. If you stop taking it earlier than advised, your symptoms may come back. This medicine is generally very... Uses of Alestin: Allergic conditions Side effects of Alestin: Sleepiness How to use Alestin: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alestin may be taken with or without food, but it is better to take it at a fixed time. How Alestin works: Alestin is an antihistaminic medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body. What if you forget to take Alestin?: If you miss a dose of Alestin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Allergic rhinitis, Allergic conditions, Chronic idiopathic urticaria Administration: May be taken with or without food. Adult Dose: Oral Allergic conditions Adult: 10-20 mg once daily. Child Dose: Oral Allergic conditions Child: >6 yr: 5 mg once daily. Contraindication: Hypersensitivity, cardiac arrhythmias. Mode of Action: Ebastine, a piperidine derivative, is a long-acting, nonsedating, second-generation histamine receptor antagonist that binds preferentially to peripheral H1 receptors. It is metabolised to active metabolite, carebastine. It has antihistaminic, antiallergic activity and prevents histamine-induced bronchoconstriction. It does not have significant sedative or antimuscarinic actions. Precaution: Caution is advised when used in hepatic impairment, renal insufficiency, QTc interval prolongation. Pregnancy, lactation. Side Effect: Headache, dry mouth, drowsiness, pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea, insomnia. Interaction: Concomitant use of ketoconazole, itraconazole, clarithromycin or erythromycin may increase plasma levels of ebastine and cause QTc interval prolongation.