Albendazole-DS - Tablet Albendazole - 400mg 10 Tablet(s) / Strip Albion Laboratories Ltd. Introduction: Albendazole-DS is an antiparasitic medicine, used for the treatment of parasitic worm infections. It works by killing the worms that cause infections and stops the infection from spreading. Albendazole-DS should be used in the dose and duration as advised by your doctor. Take it with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. Some people may experience vomiting, dizziness, increased liver enzymes, nausea and... Uses of Albendazole-DS: Parasitic worm infections Side effects of Albendazole-DS: VomitingDizzinessIncreased liver enzymesNauseaLoss of appetite How to use Albendazole-DS: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Albendazole-DS may be taken with or without food, but it is better to take it at a fixed time. How Albendazole-DS works: Albendazole-DS is an antiparasitic medication. It works by keeping the worms from absorbing sugar (glucose), thereby depleting their energy level. This causes the worms to die and treats your infection. Indication: Echinococcosis Adult: <60 kg: 15 mg/kg daily in 2 divided doses. Max: 800 mg/day. ?60 kg: 400 mg bid. Admin dose for three 28-day cycles w/ a 14-day drug-free interval in between each cycle. Neurocysticercosis Adult: <60 kg: 15 mg/kg daily in 2 divided doses (max: 800 mg/day) for 8-30 days. ?60 kg: 400 mg bid for 8-30 days. Ancylostoma, Ascariasis, Hookworm, Trichostrongylus 400 mg PO once Administration: Increased serum concentrations w/ dexamethasone, praziquantel and cimetidine. Decreased serum concentrations w/ aminoquinoline (antimalarials), carbamazepine, phenobarbital, and phenytoin. Adult Dose: Monitor blood counts and liver function. Administer within 7 days of start of normal menstruation in women of childbearing age. Adequate nonhormonal contraceptive measures must be taken during and for 1 mth after therapy. Perform liver function tests and blood counts before and every 2 wk during high dose therapy of hydatid disease. Lactation: unknown, use caution. Renal Dose: Albendazole sulfoxide (active metabolite), causes selective degeneration of cytoplasmic microtubules in intestinal and tegmental cells of intestinal helminths and larvae; glycogen is depleted, glucose uptake and cholinesterase secretion are impaired and desecratory substances accumulate intracellulary. ATP production decreases, causing energy depletion, immobilisation and worm death. Contraindication: Child: PO 15 mg/kg/day (max 800 mg/day) q12h Mode of Action: Should be taken with food. Precaution: Helminthiasis, Echinococcosis, Neurocysticercosis, Enterobiasis, Ascariasis, Hookworm infections, Strongyloidiasis, Giardiasis, Filariasis Pregnancy Category Note: >10% Headache,Neurocysticercosis (11%),Hydatid disease (1.3%),Abnormal LFT,Hydatid disease (15.6%),Neurocysticercosis (<1%) 1-10% Abdominal pain,Hydatid disease (6%),Nausea/vomiting,Hydatid disease (3.7%),Neurocysticercosis (6.2%),Dizziness/vertigo,Hydatid disease (1.2%),Neurocysticercosis (<1%),Increased intracranial pressure,Neurocysticercosis (1%),Meningeal signs,Neurocysticercosis (1%),Alopecia (reversible),Hydatid disease (1.6%),Neurocysticercosis (<1%),Fever,Hydatid disease (1%) <1% (selected) Rash,Urticaria,Agranulocytosis,Aplastic anemia,Bone marrow suppression,Granulocytopenia,Pancytopenia,Thrombocytopenia,Hepatitis,Acute liver failure,Acute renal failure Potentially Fatal: Bone marrow depression. Interaction: Pregnancy and lactation. Neonates. Hypersensitivity, liver impairment.