Act - Suspension Paracetamol - 120mg/5ml 1 60ml bot(s) / 60ml bot Ambee Pharmaceuticals Ltd. Introduction: Act 120mg/5ml is a medicine used to relieve pain and to reduce fever. It is used to treat many conditions such as headache, body ache, toothache and common cold.Act may be prescr120mg/5ml ibed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended. Side effects are rare if this medicine is used correctly but this medicine may cause stomach pain, nausea, and vomiting in some people. Consult your doctor... Uses of Act: Pain reliefFever Side effects of Act: No common side effects seen How to use Act: Take Act 120mg/5ml medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Act 120mg/5ml is to be taken with food. How Act works: Act 120mg/5ml is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever. Act is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever. What if you forget to take Act?: If you miss a dose of Act 120mg/5ml, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Indication: Fever, Mild to moderate pain, osteoarthritis, rheumatoid arthritis, chronic low back pain, Renal stone pain, neuropathic pain, toothache, migraine, postoperative mild to moderate pain. Administration: May be taken with or without food. Adult Dose: Oral Mild to moderate pain and fever Tablet Adult: 1 - 2 tablets every 4 to 6 hours up to a maximum of 4 g (8 tablets) daily Extended Release (XR) Tablet Adults: 2 tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours). Syrup/Suspension: Adults: 4-8 Measuring spoonful 3-4 times daily; Rectal Suppository Adults: 500 mg-1 g every 4-6 hours to a maximum of 4 g daily. Child Dose: Oral Mild to moderate pain and fever Tablet Children (6 - 12 years) : 1/2 to 1 tablet 3 to 4 times daily Extended Release (XR) Tablet Children over 12 years: 2 tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours). Syrup Mild to moderate pain and fever Children: 3 months - <1 year : 60 - 120 mg (1/2 - 1 measuring spoonful), 1 - 5 years : 1 - 2 measuring spoonful 6 - 12 years : 2 - 4 measuring spoonful Children: 2 months: 60 mg (1/2 measuring spoonful) for... Contraindication: Hypersensitivity. Mode of Action: Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heat-regulating centre. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS. Precaution: Patient w/ chronic alcoholism, known G6PD deficiency, severe hypovolaemia, chronic malnutrition. Renal and hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor serum paracetamol levels esp when acute overdosage is suspected and w/ long-term use. Side Effect: Thrombocytopenia, leucopenia, pancytopenia, neutropenia, agranulocytosis, pain and burning sensation at inj site. Rarely, hypotension and tachycardia. Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalised exanthematous pustulosis, acute renal tubular necrosis and hepatotoxicity. Interaction: May reduce serum levels w/ anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin and other coumarins w/ prolonged use. Accelerated absorption w/ metoclopramide and domperidone. May increase serum levels w/ probenecid. May increase serum levels of chloramphenicol. May reduce absorption w/ colestyramine w/in 1 hr of admin. May cause severe hypothermia w/ phenothiazine.